- Uploaded
- 22 Jul 2008
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- "Type III: Severe von Willebrand
disease. These people may have a total absence of von Willebrand factor
and factor VIII levels are often less than 10%."
http://www.haemophilia.org.za/Vonwil2.htm
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- "Type 3: This type of vWD is rare and
is usually associated with homozygous or compound heterozygous inheritance
of two abnormal vWF alleles. In type 3 vWD, there is a nearly complete
deficiency of vWF. vWF activity and vWF:Ag usually are undetectable, with
factor VIII levels markedly reduced to <10%. These patients have
essentially no multimers because of the marked reduction in vWF. The
incidence of type 3 vWD is 1–2 cases per one million people"
http://www.uspharmacist.com/NewLook/Ce/von/lesson.cfm
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